8QHQ
Crystal structure of human DNPH1 bound to hmdUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | polymer | 147 | 16337.4 | 6 | UniProt (O43598) Pfam (PF05014) | Homo sapiens (human) | c-Myc-responsive protein RCL |
| 2 | G, I, M, O, Q... (A, B, C, D, E...) | 5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE | non-polymer | 338.2 | 6 | Chemie (5HU) | |||
| 3 | H, J, K, L, N... (A, B, C, D, E...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | U, V, W, X, Y... (A, B, C, D, E...) | water | water | 18.0 | 498 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 19 - 162 (UniProt: O43598)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Met 18 | - | expression tag |
| Gln 104 | Glu 104 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 98024.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2525.8 | |
| All* | Total formula weight | 100550.0 |
