8QHN

Streptococcus pyogenes GapN in complex with NADPH and erythrose-4-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, E, F... (A, B, C, E, F...)	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	polymer	475	50460.5	7	UniProt (A0A4U9C786) Pfam (PF00171) UniProt (by SIFTS) (Q99Z67)	Streptococcus pyogenes
2	D (D)	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	polymer	480	51058.1	1	UniProt (A0A4U9C786) Pfam (PF00171) UniProt (by SIFTS) (Q99Z67)	Streptococcus pyogenes
3	I, L, T, W (A, B, E, F)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
4	J (A)	ERYTHOSE-4-PHOSPHATE	non-polymer		200.1	1	Chemie (E4P)
5	AA, BA, CA, DA, K... (G, H, A, B, C...)	GLYCEROL	non-polymer		92.1	17	Chemie (GOL)
6	EA, FA, GA, HA, IA... (A, B, C, D, E...)	water	water		18.0	2749	Chemie (HOH)

Sequence modifications

A, B, C, E, F, G, H: 1 - 475 (UniProt: A0A4U9C786)

PDB	External Database	Details
Thr 58	Ala 58	conflict
Ser 284	Cys 284	conflict

D: 2 - 475 (UniProt: A0A4U9C786)

PDB	External Database	Details
Ile -10	-	expression tag
Glu -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Arg -6	-	expression tag
Asp -5	-	expression tag
Thr 58	Ala 58	conflict
Ser 284	Cys 284	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	404281.3
Non-Polymers*	Number of molecules	22
	Total formula weight	4739.3
All*	Total formula weight	409020.6

*Water molecules are not included.