8QGY

Cryo-EM structure of C-terminally truncated Apoptosis signal-regulating kinase 1 (ASK1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Mitogen-activated protein kinase kinase kinase 5	polymer	896	101908.6	2	UniProt (Q99683) Pfam (PF20309) Pfam (PF13281) Pfam (PF19039) Pfam (PF00069)	Homo sapiens (human)

Sequence modifications

A, B: 88 - 976 (UniProt: Q99683)

PDB	External Database	Details
Met 87	-	initiating methionine
Arg 964	Ser 964	conflict
Asn 974	Glu 974	conflict
Ser 975	Asp 975	conflict
Ser 976	Thr 976	conflict
His 977	-	expression tag
His 978	-	expression tag
His 979	-	expression tag
His 980	-	expression tag
His 981	-	expression tag
His 982	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	203817.3
All*	Total formula weight	203817.3

*Water molecules are not included.