8Q9W
Crystal structure of HsRNMT complexed with sinefungin and GMP-PnP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | mRNA cap guanine-N7 methyltransferase | polymer | 276 | 32550.6 | 2 | UniProt (O43148) Pfam (PF03291) | Homo sapiens (human) | RG7MT1,mRNA (guanine-N(7))-methyltransferase,mRNA cap methyltransferase,hCMT1,hMet,hcm1p |
| 2 | C, E (A, B) | SINEFUNGIN | non-polymer | 381.4 | 2 | Chemie (SFG) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F (B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B: 165 - 415 (UniProt: O43148)
A, B: 456 - 476 (UniProt: O43148)
A, B: 456 - 476 (UniProt: O43148)
| PDB | External Database | Details |
|---|---|---|
| Gly 416 | - | linker |
| Leu 417 | - | linker |
| Gly 418 | - | linker |
| Cys 419 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65101.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1381.0 | |
| All* | Total formula weight | 66482.2 |
