8Q7H
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cullin-9 | polymer | 2519 | 281686.1 | 2 | UniProt (Q8IWT3) Pfam (PF11515) Pfam (PF03256) Pfam (PF00888) Pfam (PF01485) In PDB | Homo sapiens (human) | CUL-9,UbcH7-associated protein 1,p53-associated parkin-like cytoplasmic protein |
| 2 | C, D | E3 ubiquitin-protein ligase RBX1 | polymer | 108 | 12290.0 | 2 | UniProt (P62877) Pfam (PF12678) In PDB | Homo sapiens (human) | E3 ubiquitin-protein transferase RBX1,Protein ZYP,RING finger protein 75,RING-box protein 1,Rbx1,Regulator of cullins 1,ROC1 |
| 3 | N | NEDD8 | polymer | 81 | 9086.6 | 1 | UniProt (Q15843) Pfam (PF00240) In PDB | Homo sapiens (human) | Neddylin,Neural precursor cell expressed developmentally down-regulated protein 8,NEDD-8,Ubiquitin-like protein Nedd8 |
| 4 | E | Unknown | polymer | 151 | 12868.9 | 1 | Homo sapiens | ||
| 5 | A, C, D | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) |
Sequence modifications
A, B: 1 - 2517 (UniProt: Q8IWT3)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 609907.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 654.1 | |
| All* | Total formula weight | 610561.6 |
