8Q5D

PfRH5 bound to monoclonal antibody MAD10-466

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Reticulocyte-binding protein homolog 5	polymer	338	40962.4	2	UniProt (Q8IFM5) Pfam (PF18515)	Plasmodium falciparum 3D7	PfRH5
2	B, E (B, E)	Monoclonal antibody MAD10-466 heavy chain	polymer	221	23360.3	2		Homo sapiens
3	C, F (C, F)	Monoclonal antibody MAD10-466 light chain	polymer	215	23577.0	2		Homo sapiens

Sequence modifications

A, D: 140 - 297 (UniProt: Q8IFM5)

PDB	External Database	Details
Tyr 203	Cys 203	engineered mutation
Ala 216	Thr 216	engineered mutation

A, D: 298 - 526 (UniProt: Q8IFM5)

PDB	External Database	Details
Ala 299	Thr 299	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	175799.3
All*	Total formula weight	175799.3

*Water molecules are not included.