8Q44
Crystal structure of cA4-bound Can2 (E364R) in complex with oligo-T DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DUF1887 family protein | polymer | 437 | 51227.4 | 2 | UniProt (E8URK0) | Thermoanaerobacter brockii subsp. finnii Ako-1 | |
| 2 | C (C) | DNA (5'-D(*TP*TP*T)-3') | polymer | 3 | 867.6 | 1 | Thermoanaerobacter brockii subsp. finnii Ako-1 | ||
| 3 | D (X) | Cyclic tetraadenosine monophosphate (cA4) | polymer | 4 | 1271.9 | 1 | BIRD (PRD_002431) | synthetic construct | |
| 4 | E, F, G, H (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 5 | I, J, K, L (A, B, C, X) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 437 (UniProt: E8URK0)
| PDB | External Database | Details |
|---|---|---|
| Arg 364 | Glu 364 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 104594.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 219.8 | |
| All* | Total formula weight | 104814.0 |
