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8Q39

Crystal structure of YTHDC1 in complex with Compound 21 (ZA_515)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BYTH domain-containing protein 1polymer16618823.82UniProt (Q96MU7)
Pfam (PF04146)
In PDB
Homo sapiens (human)Splicing factor YT521,YT521-B
2A, B2-chloranyl-N-methyl-9-[[3-(1H-1,2,3,4-tetrazol-5-yl)phenyl]methyl]purin-6-aminenon-polymer341.82Chemie (K1O)
3A, BSULFATE IONnon-polymer96.16Chemie (SO4)
4waterwater18.0214Chemie (HOH)
Sequence modifications
A, B: 345 - 509 (UniProt: Q96MU7)
PDBExternal DatabaseDetails
Gly 344-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight37647.7
Non-Polymers*Number of molecules8
Total formula weight1259.9
All*Total formula weight38907.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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