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8Q1H

LSD1 Y391K-CoREST bound to Histone H3 N-terminal tail

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lysine-specific histone demethylase 1Apolymer73081245.41UniProt (O60341)
Pfam (PF04433)
Pfam (PF01593)
Homo sapiens (human)
2B
(B)
REST corepressor 1polymer17820244.81UniProt (Q9UKL0)
Pfam (PF20878)
Pfam (PF00249)
Homo sapiens (human)Protein CoREST
3C
(C)
Histone H3.3Cpolymer212263.71UniProt (Q6NXT2)Homo sapiensHistone H3.5
4D
(A)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
Sequence modifications
A: 123 - 852 (UniProt: O60341)
PDBExternal DatabaseDetails
Lys 391Tyr 391conflict
C: 1 - 21 (UniProt: Q6NXT2)
PDBExternal DatabaseDetails
Met 4Lys 5conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight103753.9
Non-Polymers*Number of molecules1
Total formula weight785.5
All*Total formula weight104539.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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