8PYW
Crystal structure of the human Nucleoside-diphosphate kinase B domain bound to compound diphosphate form of AT-9052-Sp.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Nucleoside diphosphate kinase B | polymer | 152 | 17249.9 | 6 | UniProt (P22392) Pfam (PF00334) | Homo sapiens (human) | NDK B,NDP kinase B,C-myc purine-binding transcription factor PUF,Histidine protein kinase NDKB,nm23-H2 |
| 2 | G, I, L (A, B, D) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | H, J, K, M, N... (A, B, C, D, E...) | [[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl] dihydrogen phosphate | non-polymer | 475.3 | 6 | Chemie (IF9) | |||
| 4 | P, Q, R, S, T... (A, B, C, D, E...) | water | water | 18.0 | 847 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 6 - 156 (UniProt: P22392)
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 103499.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 3128.0 | |
| All* | Total formula weight | 106627.5 |
