8PXV
Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Beta-N-acetylhexosaminidase | polymer | 655 | 73309.0 | 3 | UniProt (B2UN02) Pfam (PF02838) Pfam (PF00728) | Akkermansia muciniphila | |
| 2 | D, E (E, F) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 2 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | |||
| 3 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | G (C) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | H, I, J (A, B, C) | water | water | 18.0 | 456 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 647 (UniProt: B2UN02)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Leu 648 | - | expression tag |
| Glu 649 | - | expression tag |
| His 650 | - | expression tag |
| His 651 | - | expression tag |
| His 652 | - | expression tag |
| His 653 | - | expression tag |
| His 654 | - | expression tag |
| His 655 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 219927.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 684.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 115.1 | |
| All* | Total formula weight | 220726.7 |
