8PWX
PfRH5 bound to monoclonal antibody R5.008
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | scFv fragment for antibody R5.008 | polymer | 284 | 29732.1 | 1 | Homo sapiens | ||
| 2 | B (B) | Reticulocyte-binding protein homolog 5 | polymer | 338 | 40962.4 | 1 | UniProt (Q8IFM5) Pfam (PF18515) | Plasmodium falciparum 3D7 | PfRH5 |
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
B: 140 - 297 (UniProt: Q8IFM5)
B: 298 - 526 (UniProt: Q8IFM5)
| PDB | External Database | Details |
|---|---|---|
| Tyr 203 | Cys 203 | engineered mutation |
| Ala 216 | Thr 216 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 299 | Thr 299 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70694.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 70786.6 |
