8PSW
ERK2 covalently bound to RU67 cyclohexenone based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 1 | polymer | 364 | 41746.9 | 1 | UniProt (P28482) In PDB | Homo sapiens (human) | MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2 |
| 2 | A | AMP PHOSPHORAMIDATE | non-polymer | 426.2 | 1 | Chemie (AN2) | |||
| 3 | A | ~{O}3-~{tert}-butyl ~{O}1-methyl (1~{R},3~{R})-4-oxidanylidene-1-(phenylmethyl)cyclohexane-1,3-dicarboxylate | non-polymer | 346.4 | 1 | Chemie (D2I) | |||
| 4 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 1 - 360 (UniProt: P28482)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41746.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 772.6 | |
| All* | Total formula weight | 42519.6 |
