8PR2
Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, C) | C-Jun-amino-terminal kinase-interacting protein 3 | polymer | 581 | 65975.4 | 2 | UniProt (Q9UPT6) Pfam (PF09744) Pfam (PF16471) | Homo sapiens (human) | JIP-3,JNK-interacting protein 3,JNK MAP kinase scaffold protein 3,Mitogen-activated protein kinase 8-interacting protein 3 |
| 2 | C, F (f, m) | Cytoplasmic dynein 1 heavy chain 1 | polymer | 4646 | 533055.1 | 2 | UniProt (Q14204) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) Pfam (PF08385) Pfam (PF08393) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) | Homo sapiens (human) | Cytoplasmic dynein heavy chain 1,Dynein heavy chain,cytosolic |
| 3 | D (h) | Cytoplasmic dynein 1 intermediate chain 2 | polymer | 612 | 68442.1 | 1 | UniProt (Q13409) Pfam (PF11540) Pfam (PF00400) | Homo sapiens (human) | Cytoplasmic dynein intermediate chain 2,Dynein intermediate chain 2,cytosolic,DH IC-2 |
| 4 | E (j) | Cytoplasmic dynein 1 light intermediate chain 2 | polymer | 492 | 54173.2 | 1 | UniProt (O43237) Pfam (PF05783) | Homo sapiens (human) | Dynein light intermediate chain 2,cytosolic,LIC-2,LIC53/55 |
Sequence modifications
B, C: 1 - 560 (UniProt: Q9UPT6)
f, m: 1 - 4646 (UniProt: Q14204)
h: 1 - 612 (UniProt: Q13409)
| PDB | External Database | Details |
|---|---|---|
| Ser -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Gly 561 | - | expression tag |
| Ser 562 | - | expression tag |
| Gly 563 | - | expression tag |
| Ser 564 | - | expression tag |
| Gly 565 | - | expression tag |
| Arg 566 | - | expression tag |
| Trp 567 | - | expression tag |
| Ser 568 | - | expression tag |
| His 569 | - | expression tag |
| Pro 570 | - | expression tag |
| Gln 571 | - | expression tag |
| Phe 572 | - | expression tag |
| Glu 573 | - | expression tag |
| Lys 574 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu 1567 | Arg 1567 | engineered mutation |
| Glu 1610 | Lys 1610 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 484 | Thr 484 | conflict |
| Gly 499 | Asp 499 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 1320676.3 | |
| All* | Total formula weight | 1320676.3 |
