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8PQO

PITP in complex with the inhibitor VT01545

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Phosphatidylinositol transfer protein alpha isoformpolymer27131941.41UniProt (Q00169)
Pfam (PF02121)
Homo sapiens (human)PI-TP-alpha,PtdIns transfer protein alpha,PtdInsTP alpha
2B
(C)
Inhibitor VT01545polymer6707.91synthetic construct
3C
(A)
IMIDAZOLEnon-polymer69.11Chemie (IMD)
4D, E, G
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
5F
(A)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
6H, I
(A, C)
waterwater18.0236Chemie (HOH)
Sequence modifications
A: 1 - 270 (UniProt: Q00169)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32649.4
Non-Polymers*Number of molecules5
Total formula weight404.1
All*Total formula weight33053.4
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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