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8PPR

Structure of the human outer kinetochore KMN network complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(D)
Kinetochore-associated protein DSN1 homologpolymer35640122.21UniProt (Q9H410)
Pfam (PF08202)
Homo sapiens (human)
2B
(M)
Protein MIS12 homologpolymer20524170.91UniProt (Q9H081)
Pfam (PF05859)
Homo sapiens (human)
3C
(N)
Kinetochore-associated protein NSL1 homologpolymer28132209.01UniProt (Q96IY1)
Pfam (PF08641)
Homo sapiens (human)
4D
(P)
Polyamine-modulated factor 1polymer20523368.31UniProt (Q6P1K2)
Pfam (PF03980)
Homo sapiens (human)PMF-1
5E
(F)
Kinetochore protein Spc24polymer19722469.11UniProt (Q8NBT2)
Pfam (PF08286)
Homo sapiens (human)hSpc24
6F
(G)
Kinetochore protein Spc25polymer22426192.81UniProt (Q9HBM1)
Pfam (PF08234)
Homo sapiens (human)hSpc25
7G
(K)
Kinetochore scaffold 1polymer2342265722.11UniProt (Q8NG31)
Pfam (PF19221)
Pfam (PF18210)
Homo sapiens (human)ALL1-fused gene from chromosome 15q14 protein,AF15q14,Bub-linking kinetochore protein,Blinkin,Cancer susceptibility candidate gene 5 protein,Cancer/testis antigen 29,CT29,Kinetochore-null protein 1,Protein CASC5,Protein D40/AF15q14
8H
(Z)
ZW10 interactorpolymer27731333.41UniProt (O95229)
Pfam (PF15556)
Homo sapiens (human)ZW10-interacting protein 1,Zwint-1
9I
(K)
waterwater18.01Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight465587.8
All*Total formula weight465587.8
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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