8PP2

Binary crystal structure of positively supercharged ferritin variant Ftn(pos) and native(K86Q) human heavy chain ferritin (Mg formate condition)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Ferritin heavy chain, N-terminally processed	polymer	172	20360.1	6	UniProt (P02794) Pfam (PF00210) In PDB	Homo sapiens (human)
2	G, H, I, J, K...	Ferritin heavy chain, N-terminally processed	polymer	172	20115.5	6	UniProt (P02794) Pfam (PF00210) In PDB	Homo sapiens (human)
3	A, B, C, E	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
4	G, H, I, J, K...	FE (III) ION	non-polymer		55.8	12	Chemie (FE)
5	G, J, K, B, C...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
6		water	water		18.0	700	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 6 - 177 (UniProt: P02794)

PDB	External Database	Details
Lys 19	Ala 19	engineered mutation
Arg 26	Asn 26	engineered mutation
Gln 87	Lys 87	engineered mutation
Lys 91	Cys 91	engineered mutation
Arg 99	Asn 99	engineered mutation
Lys 103	Cys 103	engineered mutation
Lys 106	His 106	engineered mutation
Lys 110	Asn 110	engineered mutation
Lys 124	Asp 124	engineered mutation
Arg 163	Glu 163	engineered mutation

G, H, I, J, K, L: 6 - 177 (UniProt: P02794)

PDB	External Database	Details
Gln 87	Lys 87	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	242853.8
Non-Polymers*	Number of molecules	23
	Total formula weight	1276.4
All*	Total formula weight	244130.2

*Water molecules are not included.