8PNT
Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear cap-binding protein subunit 1 | polymer | 772 | 89781.9 | 1 | UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) | Homo sapiens (human) | 80 kDa nuclear cap-binding protein,CBP80,NCBP 80 kDa subunit |
| 2 | B (B) | Nuclear cap-binding protein subunit 2 | polymer | 156 | 18028.1 | 1 | UniProt (P52298) Pfam (PF00076) | Homo sapiens (human) | 20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1 |
| 3 | C, D (C, D) | Phosphorylated adapter RNA export protein | polymer | 394 | 44468.6 | 2 | UniProt (Q9H814) Pfam (PF10258) | Homo sapiens (human) | RNA U small nuclear RNA export adapter protein |
| 4 | E (B) | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (MGT) |
Sequence modifications
A: 20 - 790 (UniProt: Q09161)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 196747.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 539.2 | |
| All* | Total formula weight | 197286.4 |
