8PMP
Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Nuclear cap-binding protein subunit 1 | polymer | 772 | 89781.9 | 1 | UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) In PDB | Homo sapiens (human) | 80 kDa nuclear cap-binding protein,CBP80,NCBP 80 kDa subunit |
| 2 | B | Nuclear cap-binding protein subunit 2 | polymer | 156 | 18028.1 | 1 | UniProt (P52298) Pfam (PF00076) In PDB | Homo sapiens (human) | 20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1 |
| 3 | D | Serrate RNA effector molecule homolog | polymer | 729 | 83061.4 | 1 | UniProt (Q9BXP5) Pfam (PF12066) Pfam (PF04959) In PDB | Homo sapiens (human) | Arsenite-resistance protein 2 |
| 4 | B | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (MGT) |
Sequence modifications
A: 20 - 790 (UniProt: Q09161)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 190871.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 539.2 | |
| All* | Total formula weight | 191410.7 |
