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8P8A

Structure of 5D3-Fab and nanobody(Nb17)-bound ABCG2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(C, E)
5D3(Fab) light chain variable domainpolymer21423594.02Mus musculus
2B, D
(D, F)
5D3(Fab) heavy chain variable domainpolymer16017508.62Mus musculus
3E
(Z)
Nanobodypolymer12313384.81Lama glama
4F, G
(A, B)
ATP-binding cassette sub-family G member 2polymer65572385.92UniProt (Q9UNQ0)
Pfam (PF00005)
Pfam (PF19055)
Pfam (PF01061)
Homo sapiens (human)Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter
5H, I
(G, H)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight240361.8
BranchedNumber of molecules2
Total formula weight848.8
All*Total formula weight241210.6
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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