8P7W

Structure of 5D3-Fab and nanobody(Nb8)-bound ABCG2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ATP-binding cassette sub-family G member 2	polymer	655	72385.9	2	UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) In PDB	Homo sapiens (human)	Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter
2	C, Y	Nanobody	polymer	124	13481.9	2		Lama glama
3	D, F	5D3(Fab) heavy chain variable domain	polymer	221	23843.6	2		Mus musculus
4	E, G	5D3(Fab) light chain variable domain	polymer	214	23594.0	2		Mus musculus

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	266610.7
All*	Total formula weight	266610.7

*Water molecules are not included.