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8P7W

Structure of 5D3-Fab and nanobody(Nb8)-bound ABCG2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
ATP-binding cassette sub-family G member 2polymer65572385.92UniProt (Q9UNQ0)
Pfam (PF00005)
Pfam (PF19055)
Pfam (PF01061)
Homo sapiens (human)Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter
2C, H
(C, Y)
Nanobodypolymer12413481.92Lama glama
3D, F
(D, F)
5D3(Fab) heavy chain variable domainpolymer22123843.62Mus musculus
4E, G
(E, G)
5D3(Fab) light chain variable domainpolymer21423594.02Mus musculus
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight266610.7
All*Total formula weight266610.7
*Water molecules are not included.

248335

PDB entries from 2026-01-28

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