8P5R
Crystal structure of full-length, homohexameric 2-oxoglutarate dehydrogenase KGD from Mycobacterium smegmatis in complex with GarA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Multifunctional 2-oxoglutarate metabolism enzyme | polymer | 1250 | 138548.1 | 10 | UniProt (A0R2B1) Pfam (PF16078) Pfam (PF00198) Pfam (PF00676) Pfam (PF02779) Pfam (PF16870) | Mycolicibacterium smegmatis MC2 155 | 2-hydroxy-3-oxoadipate synthase,HOA synthase,HOAS,2-oxoglutarate carboxy-lyase,2-oxoglutarate decarboxylase,Alpha-ketoglutarate decarboxylase,KG decarboxylase,KGD,Alpha-ketoglutarate-glyoxylate carboligase |
| 2 | G, H, I, J, K... (G, H, I, J, K...) | Glycogen accumulation regulator GarA | polymer | 158 | 16599.0 | 6 | UniProt (A0QYG2) Pfam (PF00498) | Mycolicibacterium smegmatis MC2 155 | |
| 3 | BA, EA, HA, Q, U... (D, E, F, A, B...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | CA, FA, IA, R, T... (D, E, F, A, B...) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 5 | AA, DA, GA, JA, S... (C, D, E, F, A...) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 6 | Chemie (TPP) |
Sequence modifications
A, B, C, D, E, F, N, O, P, Q: 2 - 1227 (UniProt: A0R2B1)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Ser -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Val -8 | - | expression tag |
| Pro -7 | - | expression tag |
| Arg -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Val 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 1485075.0 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 3018.3 | |
| All* | Total formula weight | 1488093.4 |
