8P2X
Structure of human SIT1:ACE2 complex (open PD conformation)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Processed angiotensin-converting enzyme 2 | polymer | 812 | 93425.6 | 2 | UniProt (Q9BYF1) Pfam (PF01401) Pfam (PF16959) | Homo sapiens (human) | |
| 2 | C, D (C, D) | Sodium- and chloride-dependent transporter XTRP3 | polymer | 641 | 71376.3 | 2 | UniProt (Q9NP91) Pfam (PF00209) | Homo sapiens (human) | Sodium/imino-acid transporter 1,Solute carrier family 6 member 20,Transporter rB21A homolog |
| 3 | E, G (E, G) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 2 | In PDB GlyTouCan (G55220VL) | |||
| 4 | F, H (F, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, M (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | J, N (A, B) | 2-acetamido-2-deoxy-alpha-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NDG) | |||
| 7 | K, L, O, P, Q... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) |
Sequence modifications
A, B: -6 - 805 (UniProt: Q9BYF1)
C, D: 1 - 592 (UniProt: Q9NP91)
| PDB | External Database | Details |
|---|---|---|
| Asp 11 | - | insertion |
| Tyr 12 | - | insertion |
| Lys 13 | - | insertion |
| Asp 14 | - | insertion |
| Asp 15 | - | insertion |
| Asp 16 | - | insertion |
| Asp 17 | - | insertion |
| Lys 18 | Gln 18 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 593 | - | expression tag |
| Glu 594 | - | expression tag |
| Asn 595 | - | expression tag |
| Leu 596 | - | expression tag |
| Tyr 597 | - | expression tag |
| Phe 598 | - | expression tag |
| Gln 599 | - | expression tag |
| Ser 600 | - | expression tag |
| His 601 | - | expression tag |
| His 602 | - | expression tag |
| His 603 | - | expression tag |
| His 604 | - | expression tag |
| His 605 | - | expression tag |
| His 606 | - | expression tag |
| His 607 | - | expression tag |
| His 608 | - | expression tag |
| His 609 | - | expression tag |
| His 610 | - | expression tag |
| Gly 611 | - | expression tag |
| Ser 612 | - | expression tag |
| Ala 613 | - | expression tag |
| Trp 614 | - | expression tag |
| Ser 615 | - | expression tag |
| His 616 | - | expression tag |
| Pro 617 | - | expression tag |
| Gln 618 | - | expression tag |
| Phe 619 | - | expression tag |
| Glu 620 | - | expression tag |
| Lys 621 | - | expression tag |
| Gly 622 | - | expression tag |
| Gly 623 | - | expression tag |
| Gly 624 | - | expression tag |
| Ser 625 | - | expression tag |
| Gly 626 | - | expression tag |
| Gly 627 | - | expression tag |
| Gly 628 | - | expression tag |
| Ser 629 | - | expression tag |
| Gly 630 | - | expression tag |
| Gly 631 | - | expression tag |
| Ser 632 | - | expression tag |
| Ala 633 | - | expression tag |
| Trp 634 | - | expression tag |
| Ser 635 | - | expression tag |
| His 636 | - | expression tag |
| Pro 637 | - | expression tag |
| Gln 638 | - | expression tag |
| Phe 639 | - | expression tag |
| Glu 640 | - | expression tag |
| Lys 641 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 329603.7 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3319.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2342.9 | |
| All* | Total formula weight | 335265.6 |
