8P29

TEAD2 in complex with an inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Transcriptional enhancer factor TEF-4	polymer	240	27489.1	2	UniProt (Q15562) Pfam (PF17725) In PDB	Homo sapiens (human)	TEA domain family member 2,TEAD-2
2	B	MYRISTIC ACID	non-polymer		228.4	1	Chemie (MYR)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	A	5-methyl-2-[(3-phenylmethoxyphenyl)amino]benzoic acid	non-polymer		333.4	1	Chemie (WJC)
5		water	water		18.0	56	Chemie (HOH)

Sequence modifications

B, A: 217 - 456 (UniProt: Q15562)

PDB	External Database	Details
Met 216	-	initiating methionine
Val 457	-	expression tag
Glu 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	54978.2
Non-Polymers*	Number of molecules	3
	Total formula weight	653.8
All*	Total formula weight	55632.0

*Water molecules are not included.