8P29
TEAD2 in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Transcriptional enhancer factor TEF-4 | polymer | 240 | 27489.1 | 2 | UniProt (Q15562) Pfam (PF17725) | Homo sapiens (human) | TEA domain family member 2,TEAD-2 |
| 2 | C (B) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E (A) | 5-methyl-2-[(3-phenylmethoxyphenyl)amino]benzoic acid | non-polymer | 333.4 | 1 | Chemie (WJC) | |||
| 5 | F, G (B, A) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
B, A: 217 - 456 (UniProt: Q15562)
| PDB | External Database | Details |
|---|---|---|
| Met 216 | - | initiating methionine |
| Val 457 | - | expression tag |
| Glu 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
| His 461 | - | expression tag |
| His 462 | - | expression tag |
| His 463 | - | expression tag |
| His 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54978.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 653.8 | |
| All* | Total formula weight | 55632.0 |
