8P29

TEAD2 in complex with an inhibitor

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE MASSIF-1
Synchrotron site	ESRF
Beamline	MASSIF-1
Temperature [K]	100
Detector technology	PIXEL
Collection date	2022-07-04
Detector	DECTRIS PILATUS 2M
Wavelength(s)	0.966
Spacegroup name	C 1 2 1
Unit cell lengths	121.842, 61.652, 80.018
Unit cell angles	90.00, 117.51, 90.00

Refinement procedure

Resolution	57.720 - 2.060
R-factor	0.1978
Rwork	0.195
R-free	0.24010
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	0.931
Data reduction software	XDS
Data scaling software	XDS
Phasing software	PHASER
Refinement software	PHENIX ((1.20.1_4487: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	57.720	2.130
High resolution limit [Å]	2.060	2.060
Number of reflections	58253	3205
<I/σ(I)>	9.63
Completeness [%]	98.8
Redundancy	1.8
CC(1/2)	0.998	0.931

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		298	2.8M sodium formate