8P1Q
USP28 in complex with FT206
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ubiquitin carboxyl-terminal hydrolase 28 | polymer | 494 | 57883.1 | 2 | UniProt (Q96RU2) Pfam (PF00443) | Homo sapiens (human) | Deubiquitinating enzyme 28,Ubiquitin thioesterase 28,Ubiquitin-specific-processing protease 28 |
| 2 | C, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 3 | D, F (A, B) | 3-azanyl-N-[(2S)-6-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-1,2,3,4-tetrahydronaphthalen-2-yl]-6-methyl-thieno[2,3-b]pyridine-2-carboxamide | non-polymer | 447.6 | 2 | Chemie (WFT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B: 149 - 524 (UniProt: Q96RU2)
A, B: 529 - 707 (UniProt: Q96RU2)
| PDB | External Database | Details |
|---|---|---|
| Gly 148 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 525 | - | linker |
| Gly 526 | - | linker |
| Ser 527 | - | linker |
| Gly 528 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115766.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1051.5 | |
| All* | Total formula weight | 116817.7 |
