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8P1P

USP28 in complex with AZ1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BUbiquitin carboxyl-terminal hydrolase 28polymer49457924.22UniProt (Q96RU2)
Pfam (PF00443)
In PDB
Homo sapiens (human)Deubiquitinating enzyme 28,Ubiquitin thioesterase 28,Ubiquitin-specific-processing protease 28
2ACHLORIDE IONnon-polymer35.51Chemie (CL)
3ADIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
4A, B2-[[5-bromanyl-2-[[4-fluoranyl-3-(trifluoromethyl)phenyl]methoxy]phenyl]methylamino]ethanolnon-polymer422.22Chemie (WF0)
5waterwater18.047Chemie (HOH)
Sequence modifications
A, B: 149 - 524 (UniProt: Q96RU2)
PDBExternal DatabaseDetails
Gly 148-expression tag
His 280Pro 280conflict
A, B: 529 - 707 (UniProt: Q96RU2)
PDBExternal DatabaseDetails
Ser 525-linker
Gly 526-linker
Ser 527-linker
Gly 528-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight115848.3
Non-Polymers*Number of molecules4
Total formula weight958.0
All*Total formula weight116806.4
*Water molecules are not included.

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PDB entries from 2024-07-24

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