8P1M
Structure of hantaan orthohantavirus (HTNV) polymerase bound to 5'vRNA and NTP Mg
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-directed RNA polymerase L | polymer | 2196 | 251806.0 | 1 | UniProt (P23456) Pfam (PF21991) Pfam (PF12426) Pfam (PF04196) | Hantaan orthohantavirus | Protein L,Large structural protein,RdRp,Replicase,Transcriptase |
| 2 | B (D) | RNA (5'-R(P*AP*GP*UP*AP*G)-3') | polymer | 17 | 5404.2 | 1 | Hantaan orthohantavirus | ||
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A: 1 - 2151 (UniProt: P23456)
| PDB | External Database | Details |
|---|---|---|
| Met -44 | - | initiating methionine |
| Trp -43 | - | expression tag |
| Ser -42 | - | expression tag |
| His -41 | - | expression tag |
| Pro -40 | - | expression tag |
| Gln -39 | - | expression tag |
| Phe -38 | - | expression tag |
| Glu -37 | - | expression tag |
| Lys -36 | - | expression tag |
| Gly -35 | - | expression tag |
| Gly -34 | - | expression tag |
| Gly -33 | - | expression tag |
| Ser -32 | - | expression tag |
| Gly -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ser -28 | - | expression tag |
| Gly -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Ser -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Ala -23 | - | expression tag |
| Trp -22 | - | expression tag |
| Ser -21 | - | expression tag |
| His -20 | - | expression tag |
| Pro -19 | - | expression tag |
| Gln -18 | - | expression tag |
| Phe -17 | - | expression tag |
| Glu -16 | - | expression tag |
| Lys -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ala 97 | Asp 97 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 257210.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 555.8 | |
| All* | Total formula weight | 257766.1 |
