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8P1M

Structure of hantaan orthohantavirus (HTNV) polymerase bound to 5'vRNA and NTP Mg

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001172biological_processRNA-templated transcription
A0003968molecular_functionRNA-directed RNA polymerase activity
A0004518molecular_functionnuclease activity
A0004519molecular_functionendonuclease activity
A0006351biological_processDNA-templated transcription
A0016740molecular_functiontransferase activity
A0016779molecular_functionnucleotidyltransferase activity
A0016787molecular_functionhydrolase activity
A0019079biological_processviral genome replication
A0030430cellular_componenthost cell cytoplasm
A0034062molecular_function5'-3' RNA polymerase activity
A0039689biological_processnegative stranded viral RNA replication
A0039694biological_processviral RNA genome replication
A0039696biological_processRNA-templated viral transcription
A0044220cellular_componenthost cell perinuclear region of cytoplasm
A0046872molecular_functionmetal ion binding
A0075526biological_processcap snatching
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues186
DetailsDomain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"I0DF35","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

238895

PDB entries from 2025-07-16

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