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8P1M

Structure of hantaan orthohantavirus (HTNV) polymerase bound to 5'vRNA and NTP Mg

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001172biological_processRNA-templated transcription
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0004519molecular_functionendonuclease activity
A0030430cellular_componenthost cell cytoplasm
A0034062molecular_function5'-3' RNA polymerase activity
A0039689biological_processnegative stranded viral RNA replication
A0039696biological_processRNA-templated viral transcription
A0044220cellular_componenthost cell perinuclear region of cytoplasm
A0046872molecular_functionmetal ion binding
A0075526biological_processcap snatching
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: For endonuclease activity => ECO:0000305|PubMed:27304209
ChainResidueDetails
ALYS124

site_idSWS_FT_FI2
Number of Residues5
DetailsBINDING: BINDING => ECO:0000269|PubMed:27304209
ChainResidueDetails
AHIS36
AGLU54
AALA97
AGLU110
AVAL111

site_idSWS_FT_FI3
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:I0DF35
ChainResidueDetails
AASP1099

226707

PDB entries from 2024-10-30

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