8P0Z

AP01-S2.3 - a variant of a redesigned transferrin receptor apical domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transferrin receptor protein 1, serum form	polymer	168	18180.6	1	UniProt (P02786) Pfam (PF02225) In PDB	Homo sapiens (human)	sTfR
2	A	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
3	A	BORIC ACID	non-polymer		61.8	1	Chemie (BO3)
4		water	water		18.0	108	Chemie (HOH)

Sequence modifications

A: 2 - 104 (UniProt: P02786)

PDB	External Database	Details
Met 1	-	initiating methionine
Glu 15	Val 210	conflict
Ser 24	Tyr 219	conflict
Asn 27	Tyr 222	conflict
Thr 103	Phe 298	conflict

A: 110 - 155 (UniProt: P02786)

PDB	External Database	Details
Lys 105	-	linker
Gly 106	-	linker
Lys 107	-	linker
Ser 108	-	linker
Gly 109	-	linker
Glu 118	Ala 340	conflict
Gly 156	-	expression tag
Gly 157	-	expression tag
Arg 158	-	expression tag
Gly 159	-	expression tag
Ser 160	-	expression tag
Leu 161	-	expression tag
Glu 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	18180.6
Non-Polymers*	Number of molecules	3
	Total formula weight	107.8
All*	Total formula weight	18288.4

*Water molecules are not included.