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8OXD

Structure of the human LYVE-1 (lymphatic vessel endothelial receptor-1) hyaluronan binding domain bound with decasaccharide hyaluronan.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lymphatic vessel endothelial hyaluronic acid receptor 1polymer14616102.71UniProt (Q9Y5Y7)
Pfam (PF00193)
Homo sapiens (human)LYVE-1,Cell surface retention sequence-binding protein 1,CRSBP-1,Extracellular link domain-containing protein 1,Hyaluronic acid receptor
2B
(C)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acidbranched1156.01In PDB
GlyTouCan (G97733LD)
3C, D, E
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
4F
(A)
waterwater18.091Chemie (HOH)
Sequence modifications
A: 1 - 144 (UniProt: Q9Y5Y7)
PDBExternal DatabaseDetails
His 145-expression tag
His 146-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16102.7
BranchedNumber of molecules1
Total formula weight1156.0
Non-Polymers*Number of molecules3
Total formula weight663.6
All*Total formula weight17922.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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