8OW1

Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Centromere-binding protein 1	polymer	351	39444.7	2	UniProt (P17106) Pfam (PF00010) In PDB	Saccharomyces cerevisiae (baker's yeast)	CBP-1,Centromere promoter factor 1,Centromere-binding factor 1
2	I, II	Inner kinetochore subunit CTF3	polymer	733	84345.6	2	UniProt (Q12748) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-I homolog,Chromosome loss protein 3,Chromosome transmission fidelity protein 3,Constitutive centromere-associated network protein CTF3
3	K, KK	Inner kinetochore subunit MCM22	polymer	239	27602.5	2	UniProt (P47167) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-K homolog,Constitutive centromere-associated network protein MCM22,Minichromosome maintenance protein 22
4	H, HH	Inner kinetochore subunit MCM16	polymer	181	21166.1	2	UniProt (Q12262) Pfam (PF20993) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-H homolog,Constitutive centromere-associated network protein MCM16,Minichromosome maintenance protein 16
5	LL, L	Inner kinetochore subunit IML3	polymer	245	28093.2	2	UniProt (P38265) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-L homolog,Constitutive centromere-associated network protein IML3,Increased minichromosome loss protein 3,Minichromosome maintenance protein 19
6	NN, N	Inner kinetochore subunit CHL4	polymer	458	52743.7	2	UniProt (P38907) Pfam (PF05238) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-N homolog,Chromosome loss protein 4,Chromosome transmission fidelity protein 17,Constitutive centromere-associated network protein CHL4,Minichromosome maintenance protein 17
7	CT	Centromere DNA-binding protein complex CBF3 subunit C	polymer	478	56416.9	1	UniProt (P35203) In PDB	Saccharomyces cerevisiae (baker's yeast)	Chromosome transmission fidelity protein 13,Kinetochore protein CTF13
8	ce, CE	Centromere DNA-binding protein complex CBF3 subunit B	polymer	608	71439.9	2	UniProt (P40969) Pfam (PF00172) Pfam (PF16846) In PDB	Saccharomyces cerevisiae (baker's yeast)	Centromere protein 3
9	SK	Suppressor of kinetochore protein 1	polymer	194	22357.3	1	UniProt (P52286) Pfam (PF03931) Pfam (PF01466) In PDB	Saccharomyces cerevisiae (baker's yeast)	Centromere DNA-binding protein complex CBF3 subunit D,E3 ubiquitin ligase complex SCF subunit SKP1
10	P, PP	Inner kinetochore subunit CTF19	polymer	369	42841.1	2	UniProt (Q02732) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-P homolog,Chromosome transmission fidelity protein 19,Constitutive centromere-associated network protein CTF19,Minichromosome maintenance protein 18
11	Q, QQ	Inner kinetochore subunit OKP1	polymer	406	47427.2	2	UniProt (P53298) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-Q homolog,Constitutive centromere-associated network protein OKP1,Outer kinetochore protein 1
12	OO, O	Inner kinetochore subunit MCM21	polymer	368	43028.9	2	UniProt (Q06675) Pfam (PF09496) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-O homolog,Chromosome transmission fidelity protein 5,Constitutive centromere-associated network protein MCM21,Minichromosome maintenance protein 21
13	T, TT	Inner kinetochore subunit CNN1	polymer	361	41359.8	2	UniProt (P43618) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-T homolog,Co-purified with NNF1 protein 1,Constitutive centromere-associated network protein CNN1
14	U, UU	Inner kinetochore subunit AME1	polymer	324	37506.7	2	UniProt (P38313) Pfam (PF20994) In PDB	Saccharomyces cerevisiae (baker's yeast)	Associated with microtubules and essential protein 1,CENP-U homolog,Constitutive centromere-associated network protein AME1
15	W, WW	Inner kinetochore subunit WIP1	polymer	89	10255.5	2	UniProt (Q2V2P8) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-W homolog,Constitutive centromere-associated network protein WIP1,W-like protein 1
16	Y, YY	Inner kinetochore subunit NKP1	polymer	238	27006.5	2	UniProt (Q12493) In PDB	Saccharomyces cerevisiae (baker's yeast)	Constitutive centromere-associated network protein NKP1,Non-essential kinetochore protein 1
17	Z, ZZ	Inner kinetochore subunit NKP2	polymer	153	17877.0	2	UniProt (Q06162) Pfam (PF09447) In PDB	Saccharomyces cerevisiae (baker's yeast)	Constitutive centromere-associated network protein NKP2,Non-essential kinetochore protein 2
18	D	C0N3	polymer	153	47239.3	1		Saccharomyces cerevisiae
19	E	C0N3	polymer	153	47194.2	1		Saccharomyces cerevisiae
20	b, f	Histone H4	polymer	103	11395.4	2	UniProt (P02309) Pfam (PF15511) In PDB	Saccharomyces cerevisiae (baker's yeast)
21	d, h	Histone H2B.1	polymer	131	14280.4	2	UniProt (P02293) Pfam (PF00125) In PDB	Saccharomyces cerevisiae (baker's yeast)	Suppressor of Ty protein 12
22	e, a	Histone H3-like centromeric protein CSE4	polymer	229	26885.4	2	UniProt (P36012) Pfam (PF00125) In PDB	Saccharomyces cerevisiae (baker's yeast)	CENP-A homolog,CENPA homolog,Chromosome segregation protein 4
23	g, c	Histone H2A.1	polymer	132	14013.2	2	UniProt (P04911) Pfam (PF00125) Pfam (PF16211) In PDB	Saccharomyces cerevisiae (baker's yeast)

Contents of the asymmetric unit

Polymers	Number of chains	42
	Total formula weight	1490633.4
All*	Total formula weight	1490633.4

*Water molecules are not included.