8OU3
Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 8d
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cereblon isoform 4 | polymer | 125 | 13703.6 | 3 | UniProt (A4TVL0) | Magnetospirillum gryphiswaldense | |
| 2 | D, G, J (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E, K (A, C) | S-Thalidomide | non-polymer | 258.2 | 2 | Chemie (EF2) | |||
| 4 | F, I, L (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 5 | H (B) | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-fluoranyl-benzamide | non-polymer | 265.2 | 1 | Chemie (W1T) | |||
| 6 | M, N, O (A, B, C) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41110.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1262.8 | |
| All* | Total formula weight | 42373.6 |
