8OSK
Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL+5.8 (composite map)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E (A, E) | Histone H3.1 | polymer | 139 | 15719.4 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
2 | B, F (B, F) | Histone H4 | polymer | 106 | 11676.7 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
3 | C, G (C, G) | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
4 | D, H (D, H) | Histone H2B type 1-J | polymer | 128 | 14088.3 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1,Histone H2B.r,H2B/r |
5 | I (I) | DNA (124-MER) | polymer | 153 | 46975.9 | 1 | synthetic construct | ||
6 | J (J) | DNA (124-MER) | polymer | 153 | 47483.2 | 1 | synthetic construct | ||
7 | K (M) | Circadian locomoter output cycles protein kaput | polymer | 375 | 43768.4 | 1 | UniProt (O08785) Pfam (PF00010) Pfam (PF00989) Pfam (PF14598) | Mus musculus (house mouse) | mCLOCK |
8 | L (N) | Basic helix-loop-helix ARNT-like protein 1 | polymer | 384 | 43821.2 | 1 | UniProt (Q9WTL8) Pfam (PF00989) Pfam (PF14598) Pfam (PF00010) | Mus musculus (house mouse) | Arnt3,Aryl hydrocarbon receptor nuclear translocator-like protein 1,Brain and muscle ARNT-like 1 |
Sequence modifications
A, E: 0 - 135 (UniProt: P68431)
B, F: 0 - 102 (UniProt: P62805)
C, G: 0 - 129 (UniProt: P04908)
D, H: 0 - 124 (UniProt: P06899)
M: 26 - 395 (UniProt: O08785)
N: 69 - 447 (UniProt: Q9WTL8)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 21 | - | expression tag |
Ala 22 | - | expression tag |
Met 23 | - | expression tag |
Asn 24 | - | expression tag |
Pro 25 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 64 | - | expression tag |
Ala 65 | - | expression tag |
Met 66 | - | expression tag |
Asn 67 | - | expression tag |
Pro 68 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 293913.3 | |
All* | Total formula weight | 293913.3 |