8OR2
CAND1-CUL1-RBX1-DCNL1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cullin-1 | polymer | 813 | 93730.7 | 1 | UniProt (Q13616) Pfam (PF00888) Pfam (PF10557) | Homo sapiens (human) | CUL-1 |
| 2 | B (B) | E3 ubiquitin-protein ligase RBX1 | polymer | 108 | 12290.0 | 1 | UniProt (P62877) Pfam (PF12678) | Homo sapiens (human) | E3 ubiquitin-protein transferase RBX1,Protein ZYP,RING finger protein 75,RING-box protein 1,Rbx1,Regulator of cullins 1,ROC1 |
| 3 | C (C) | Cullin-associated NEDD8-dissociated protein 1 | polymer | 1238 | 137358.2 | 1 | UniProt (Q86VP6) Pfam (PF13513) Pfam (PF08623) | Homo sapiens (human) | Cullin-associated and neddylation-dissociated protein 1,TBP-interacting protein of 120 kDa A,TBP-interacting protein 120A,p120 CAND1 |
| 4 | D (F) | DCN1-like protein 1 | polymer | 261 | 30304.4 | 1 | UniProt (Q96GG9) Pfam (PF14555) Pfam (PF03556) | Homo sapiens (human) | DCNL1,DCUN1 domain-containing protein 1,Defective in cullin neddylation protein 1-like protein 1,Squamous cell carcinoma-related oncogene |
| 5 | E, F, G (B) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 1 - 776 (UniProt: Q13616)
C: 1 - 1230 (UniProt: Q86VP6)
F: 1 - 259 (UniProt: Q96GG9)
| PDB | External Database | Details |
|---|---|---|
| Met -36 | - | initiating methionine |
| Trp -35 | - | expression tag |
| Ser -34 | - | expression tag |
| His -33 | - | expression tag |
| Pro -32 | - | expression tag |
| Gln -31 | - | expression tag |
| Phe -30 | - | expression tag |
| Glu -29 | - | expression tag |
| Lys -28 | - | expression tag |
| Gly -27 | - | expression tag |
| Ser -26 | - | expression tag |
| Ala -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Ser -23 | - | expression tag |
| Ala -22 | - | expression tag |
| Ala -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ala -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Trp -15 | - | expression tag |
| Ser -14 | - | expression tag |
| His -13 | - | expression tag |
| Pro -12 | - | expression tag |
| Gln -11 | - | expression tag |
| Phe -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Ser -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Glu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 273683.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 273879.5 |
