8OQ7
CryoEM structure of human rho1 GABAA receptor in complex with inhibitor TPMPA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Gamma-aminobutyric acid receptor subunit rho-1 | polymer | 479 | 55950.2 | 5 | UniProt (P24046) Pfam (PF02931) Pfam (PF02932) In PDB | Homo sapiens (human) | GABA(A) receptor subunit rho-1,GABA(C) receptor |
| 2 | E, C, A, D, B | methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid | non-polymer | 161.1 | 5 | Chemie (VZA) | |||
| 3 | E, C, A, D, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 4 | E, C, A, D, B | HEXANE | non-polymer | 86.2 | 15 | Chemie (HEX) | |||
| 5 | E, C, A, D, B | N-OCTANE | non-polymer | 114.2 | 5 | Chemie (OCT) | |||
| 6 | B, E, C, A, D | DODECANE | non-polymer | 170.3 | 10 | Chemie (D12) | |||
| 7 | B, C, E, A, D | DECANE | non-polymer | 142.3 | 10 | Chemie (D10) | |||
| 8 | B, A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | water | water | 18.0 | 505 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 279751.2 | |
| Non-Polymers* | Number of molecules | 57 |
| Total formula weight | 8078.6 | |
| All* | Total formula weight | 287829.8 |
