8OQ7
CryoEM structure of human rho1 GABAA receptor in complex with inhibitor TPMPA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Gamma-aminobutyric acid receptor subunit rho-1 | polymer | 479 | 55950.2 | 5 | UniProt (P24046) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit rho-1,GABA(C) receptor |
| 2 | AB, EA, F, PA, S (E, C, A, D, B) | methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid | non-polymer | 161.1 | 5 | Chemie (VZA) | |||
| 3 | BB, CB, FA, G, GA... (E, C, A, D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 4 | DB, EB, FB, HA, I... (E, C, A, D, B) | HEXANE | non-polymer | 86.2 | 15 | Chemie (HEX) | |||
| 5 | GB, KA, L, VA, Y (E, C, A, D, B) | N-OCTANE | non-polymer | 114.2 | 5 | Chemie (OCT) | |||
| 6 | BA, HB, JB, LA, M... (B, E, C, A, D) | DODECANE | non-polymer | 170.3 | 10 | Chemie (D12) | |||
| 7 | AA, DA, IB, MA, N... (B, C, E, A, D) | DECANE | non-polymer | 142.3 | 10 | Chemie (D10) | |||
| 8 | CA, Q (B, A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | KB, LB, MB, NB, OB (A, B, C, D, E) | water | water | 18.0 | 505 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 279751.2 | |
| Non-Polymers* | Number of molecules | 57 |
| Total formula weight | 8078.6 | |
| All* | Total formula weight | 287829.8 |
