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8OMZ

Wide inward-open unliganded UraA in complex with a conformation-selective synthetic nanobody

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Uracil permeasepolymer43746017.92UniProt (P0AGM7)
Pfam (PF00860)
Escherichia coli O157:H7Uracil transporter,Uracil/H(+) symporter UraA
2B, D
(B, D)
Sy45polymer15416668.32synthetic construct
3E, P
(A, C)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.12Chemie (TRS)
4F, G, H, I, J...
(A, C)
nonyl beta-D-glucopyranosidenon-polymer306.411Chemie (BNG)
5L, T
(A, C)
PENTAETHYLENE GLYCOLnon-polymer238.32Chemie (1PE)
6N, O, V
(A, B, D)
DECYL-BETA-D-MALTOPYRANOSIDEnon-polymer482.63Chemie (DMU)
Sequence modifications
A, C: 2 - 429 (UniProt: P0AGM7)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Ser 1-expression tag
Pro 320Gly 320engineered mutation
Ala 430-expression tag
Leu 431-expression tag
Glu 432-expression tag
Val 433-expression tag
Leu 434-expression tag
Phe 435-expression tag
Gln 436-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight125372.4
Non-Polymers*Number of molecules18
Total formula weight5538.9
All*Total formula weight130911.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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