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8OL9

Anti-FIXa Fab in complex with human des-(Gla-EGF1) FIXa

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Light chain of FIXa binding Fabpolymer21423461.01Homo sapiens
2B
(B)
Heavy chain of FIXa binding Fabpolymer22524030.91Homo sapiens
3C
(H)
Coagulation factor IX heavy chainpolymer23526190.81UniProt (P00740)
Pfam (PF00089)
Homo sapiens (human)Christmas factor,Plasma thromboplastin component,PTC
4D
(L)
Coagulation factor IX light chainpolymer596470.41UniProt (P00740)
Pfam (PF14670)
Homo sapiens (human)Christmas factor,Plasma thromboplastin component,PTC
5E, G
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
6F
(A)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
7H
(H)
CALCIUM IONnon-polymer40.11Chemie (CA)
8I
(H)
L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamidenon-polymer395.91Chemie (0GJ)
9J, K, L, M
(A, B, H, L)
waterwater18.037Chemie (HOH)
Sequence modifications
L: 2 - 59 (UniProt: P00740)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight80153.1
Non-Polymers*Number of molecules5
Total formula weight750.2
All*Total formula weight80903.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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