8OIS
28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (BX) | 39S ribosomal protein L19, mitochondrial | polymer | 292 | 33585.0 | 1 | UniProt (P49406) Pfam (PF01245) | Homo sapiens (human) | MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m |
| 2 | B (Bd) | 39S ribosomal protein L55, mitochondrial | polymer | 128 | 15160.4 | 1 | UniProt (Q7Z7F7) Pfam (PF09776) | Homo sapiens (human) | MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55 |
| 3 | C (AA) | 12S rRNA | polymer | 955 | 306547.5 | 1 | GenBank (OM714795.1) | Homo sapiens (human) | |
| 4 | D (AB) | 28S ribosomal protein S35, mitochondrial | polymer | 323 | 36898.3 | 1 | UniProt (P82673) Pfam (PF10213) | Homo sapiens (human) | MRP-S35,S35mt,28S ribosomal protein S28,mitochondrial,MRP-S28,S28mt,Mitochondrial small ribosomal subunit protein mS35 |
| 5 | E (AC) | 28S ribosomal protein S24, mitochondrial | polymer | 167 | 19046.2 | 1 | UniProt (Q96EL2) Pfam (PF14955) | Homo sapiens (human) | MRP-S24,S24mt,Mitochondrial small ribosomal subunit protein uS3m,bMRP-47,bMRP47 |
| 6 | F (AD) | Aurora kinase A-interacting protein | polymer | 199 | 22395.3 | 1 | UniProt (Q9NWT8) Pfam (PF08213) | Homo sapiens (human) | AURKA-interacting protein,28S ribosomal protein S38,mitochondrial,MRP-S38,Mitochondrial small ribosomal subunit protein mS38 |
| 7 | G (AE) | 28S ribosomal protein S6, mitochondrial | polymer | 125 | 14250.6 | 1 | UniProt (P82932) Pfam (PF01250) | Homo sapiens (human) | MRP-S6,S6mt,Mitochondrial small ribosomal subunit protein bS6m |
| 8 | H (AF) | 28S ribosomal protein S7, mitochondrial | polymer | 242 | 28186.2 | 1 | UniProt (Q9Y2R9) Pfam (PF00177) | Homo sapiens (human) | MRP-S7,S7mt,Mitochondrial small ribosomal subunit protein uS7m,bMRP-27a,bMRP27a |
| 9 | I (AG) | P-site Met-tRNA(Met) | polymer | 71 | 22692.5 | 1 | GenBank (NC_012920.1) | Homo sapiens (human) | |
| 10 | J (AH) | 28S ribosomal protein S10, mitochondrial | polymer | 201 | 23033.5 | 1 | UniProt (P82664) Pfam (PF00338) | Homo sapiens (human) | MRP-S10,S10mt,Mitochondrial small ribosomal subunit protein uS10m |
| 11 | K (AI) | mRNA | polymer | 33 | 7329.9 | 1 | Homo sapiens | ||
| 12 | L (AJ) | 28S ribosomal protein S12, mitochondrial | polymer | 138 | 15200.9 | 1 | UniProt (O15235) Pfam (PF00164) | Homo sapiens (human) | MRP-S12,S12mt,MT-RPS12,Mitochondrial small ribosomal subunit protein uS12m |
| 13 | M (AK) | 28S ribosomal protein S14, mitochondrial | polymer | 128 | 15168.8 | 1 | UniProt (O60783) Pfam (PF00253) | Homo sapiens (human) | MRP-S14,S14mt,Mitochondrial small ribosomal subunit protein uS14m |
| 14 | N (AL) | 28S ribosomal protein S15, mitochondrial | polymer | 257 | 29903.3 | 1 | UniProt (P82914) Pfam (PF00312) | Homo sapiens (human) | MRP-S15,S15mt,Mitochondrial small ribosomal subunit protein uS15m |
| 15 | O (AM) | 28S ribosomal protein S16, mitochondrial | polymer | 137 | 15371.9 | 1 | UniProt (Q9Y3D3) Pfam (PF00886) | Homo sapiens (human) | MRP-S16,S16mt,Mitochondrial small ribosomal subunit protein bS16m |
| 16 | P (AN) | 28S ribosomal protein S17, mitochondrial | polymer | 130 | 14526.1 | 1 | UniProt (Q9Y2R5) Pfam (PF00366) | Homo sapiens (human) | MRP-S17,S17mt,Mitochondrial small ribosomal subunit protein uS17m |
| 17 | Q (AO) | 28S ribosomal protein S18b, mitochondrial | polymer | 258 | 29440.6 | 1 | UniProt (Q9Y676) Pfam (PF01084) | Homo sapiens (human) | MRP-S18-b,Mrps18-b,S18mt-b,28S ribosomal protein S18-2,mitochondrial,MRP-S18-2,Mitochondrial small ribosomal subunit protein bS18b,Mitochondrial small ribosomal subunit protein mS40 |
| 18 | R (AP) | 28S ribosomal protein S18c, mitochondrial | polymer | 142 | 15876.8 | 1 | UniProt (Q9Y3D5) Pfam (PF01084) | Homo sapiens (human) | MRP-S18-c,Mrps18-c,S18mt-c,28S ribosomal protein S18-1,mitochondrial,MRP-S18-1,Mitochondrial small ribosomal subunit protein bS18c,Mitochondrial small ribosomal subunit protein bS18m |
| 19 | S (AQ) | 28S ribosomal protein S21, mitochondrial | polymer | 87 | 10806.7 | 1 | UniProt (P82921) Pfam (PF01165) | Homo sapiens (human) | MRP-S21,S21mt,Mitochondrial small ribosomal subunit protein bS21m |
| 20 | T (AR) | 28S ribosomal protein S22, mitochondrial | polymer | 360 | 41337.3 | 1 | UniProt (P82650) Pfam (PF10245) | Homo sapiens (human) | MRP-S22,S22mt,Mitochondrial small ribosomal subunit protein mS22 |
| 21 | U (AS) | 28S ribosomal protein S23, mitochondrial | polymer | 190 | 21805.7 | 1 | UniProt (Q9Y3D9) Pfam (PF10484) | Homo sapiens (human) | MRP-S23,S23mt,Mitochondrial small ribosomal subunit protein mS23 |
| 22 | V (AT) | 28S ribosomal protein S25, mitochondrial | polymer | 173 | 20146.4 | 1 | UniProt (P82663) Pfam (PF05047) | Homo sapiens (human) | MRP-S25,S25mt,Mitochondrial small ribosomal subunit protein mS25 |
| 23 | W (AU) | 28S ribosomal protein S26, mitochondrial | polymer | 205 | 24259.8 | 1 | UniProt (Q9BYN8) Pfam (PF14943) | Homo sapiens (human) | MRP-S26,S26mt,28S ribosomal protein S13,mitochondrial,MRP-S13,S13mt,Mitochondrial small ribosomal subunit protein mS26 |
| 24 | X (AV) | 28S ribosomal protein S27, mitochondrial | polymer | 414 | 47669.3 | 1 | UniProt (Q92552) Pfam (PF10037) | Homo sapiens (human) | MRP-S27,S27mt,Mitochondrial ribosomal protein S27,Mitochondrial small ribosomal subunit protein mS27 |
| 25 | Y (AW) | 28S ribosomal protein S28, mitochondrial | polymer | 187 | 20878.8 | 1 | UniProt (Q9Y2Q9) Pfam (PF10246) | Homo sapiens (human) | MRP-S28,S28mt,28S ribosomal protein S35,mitochondrial,MRP-S35,S35mt,Mitochondrial small ribosomal subunit protein bS1m |
| 26 | Z (AX) | 28S ribosomal protein S29, mitochondrial | polymer | 398 | 45634.4 | 1 | UniProt (P51398) Pfam (PF10236) | Homo sapiens (human) | MRP-S29,S29mt,Death-associated protein 3,DAP-3,Ionizing radiation resistance conferring protein,Mitochondrial small ribosomal subunit protein mS29 |
| 27 | AA (AY) | 28S ribosomal protein S31, mitochondrial | polymer | 395 | 45391.5 | 1 | UniProt (Q92665) Pfam (PF15433) | Homo sapiens (human) | MRP-S31,S31mt,Imogen 38,Mitochondrial small ribosomal subunit protein mS31 |
| 28 | BA (AZ) | 28S ribosomal protein S33, mitochondrial | polymer | 106 | 12657.8 | 1 | UniProt (Q9Y291) Pfam (PF08293) | Homo sapiens (human) | MRP-S33,S33mt,Mitochondrial small ribosomal subunit protein mS33 |
| 29 | CA (Aa) | Peptide chain release factor 1, mitochondrial,mtRF1(AAQ) | polymer | 484 | 56258.4 | 1 | UniProt (O75570) Pfam (PF03462) Pfam (PF00472) | Homo sapiens (human) | MRF-1,MtRF-1 |
| 30 | DA (Ab) | 28S ribosomal protein S2, mitochondrial | polymer | 296 | 33298.2 | 1 | UniProt (Q9Y399) Pfam (PF00318) | Homo sapiens (human) | MRP-S2,S2mt,Mitochondrial small ribosomal subunit protein uS2m |
| 31 | EA (Ac) | Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 | polymer | 118 | 13540.9 | 1 | UniProt (Q96BP2) Pfam (PF06747) | Homo sapiens (human) | 28S ribosomal protein S37,mitochondrial,MRP-S37,Mitochondrial small ribosomal subunit protein mS37,Nuclear protein C2360 |
| 32 | FA (Ad) | 28S ribosomal protein S5, mitochondrial | polymer | 430 | 48094.6 | 1 | UniProt (P82675) Pfam (PF21251) Pfam (PF00333) Pfam (PF03719) | Homo sapiens (human) | MRP-S5,S5mt,Mitochondrial small ribosomal subunit protein uS5m |
| 33 | GA (Ae) | Pentatricopeptide repeat domain-containing protein 3, mitochondrial | polymer | 689 | 78648.5 | 1 | UniProt (Q96EY7) Pfam (PF22330) Pfam (PF13812) | Homo sapiens (human) | 28S ribosomal protein S39,mitochondrial,MRP-S39,Mitochondrial small ribosomal subunit protein mS39,Transformation-related gene 15 protein,TRG-15 |
| 34 | HA (Ag) | 28S ribosomal protein S9, mitochondrial | polymer | 396 | 45909.9 | 1 | UniProt (P82933) Pfam (PF00380) | Homo sapiens (human) | MRP-S9,S9mt,Mitochondrial small ribosomal subunit protein uS9m |
| 35 | IA (Ai) | 28S ribosomal protein S11, mitochondrial | polymer | 194 | 20663.8 | 1 | UniProt (P82912) Pfam (PF00411) | Homo sapiens (human) | MRP-S11,S11mt,Cervical cancer proto-oncogene 2 protein,HCC-2,Mitochondrial small ribosomal subunit protein uS11m |
| 36 | JA (Aj) | 28S ribosomal protein S34, mitochondrial | polymer | 218 | 25695.5 | 1 | UniProt (P82930) Pfam (PF16053) | Homo sapiens (human) | S34mt,Mitochondrial small ribosomal subunit protein mS34 |
| 37 | CG, KA, LA, MA, NA... (Ae, AA) | POTASSIUM ION | non-polymer | 39.1 | 17 | Chemie (K) | |||
| 38 | AB, AC, AD, AE, AF... (AA, Ab, Ad, AD, AG...) | MAGNESIUM ION | non-polymer | 24.3 | 126 | Chemie (MG) | |||
| 39 | RF (AG) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 40 | TF (AO) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 41 | UF, VF (AP, AT) | FE-S-O HYBRID CLUSTER | non-polymer | 335.5 | 2 | Chemie (FS2) | |||
| 42 | XF (AX) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 43 | ZF (AX) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 44 | DG (AX) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
AA: 1 - 955 (GenBank: OM714795.1)
AG: 1 - 71 (GenBank: NC_012920.1)
AQ: 1 - 87 (UniProt: P82921)
Aa: 1 - 445 (UniProt: O75570)
Aa: 446 - 484 (PDB: 8OIS)
Ai: 1 - 194 (UniProt: P82912)
| PDB | External Database | Details |
|---|---|---|
| G 62 | A 710 | variant |
| PDB | External Database | Details |
|---|---|---|
| C 69 | - | insertion |
| C 70 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Arg 50 | Cys 50 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ala 311 | Gly 311 | engineered mutation |
| Ala 312 | Gly 312 | engineered mutation |
Ai: 1 - 194 (UniProt: P82912)
| PDB | External Database | Details |
|---|---|---|
| 5f0 184 | Asn 184 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 36 |
| Total formula weight | 1277311.3 | |
| Non-Polymers* | Number of molecules | 149 |
| Total formula weight | 5563.1 | |
| All* | Total formula weight | 1282874.5 |
