Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8OIS

28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0003747	molecular_function	translation release factor activity
Aa	0005737	cellular_component	cytoplasm
Aa	0005739	cellular_component	mitochondrion
Aa	0005759	cellular_component	mitochondrial matrix
Aa	0006412	biological_process	translation
Aa	0006415	biological_process	translational termination
Aa	0016149	molecular_function	translation release factor activity, codon specific
Aa	0070126	biological_process	mitochondrial translational termination
Ab	0003735	molecular_function	structural constituent of ribosome
Ab	0005739	cellular_component	mitochondrion
Ab	0005743	cellular_component	mitochondrial inner membrane
Ab	0005759	cellular_component	mitochondrial matrix
Ab	0005763	cellular_component	mitochondrial small ribosomal subunit
Ab	0005840	cellular_component	ribosome
Ab	0006412	biological_process	translation
Ab	0015935	cellular_component	small ribosomal subunit
Ab	0032543	biological_process	mitochondrial translation
Ab	0061668	biological_process	mitochondrial ribosome assembly
Ab	1990904	cellular_component	ribonucleoprotein complex
AB	0003723	molecular_function	RNA binding
AB	0003735	molecular_function	structural constituent of ribosome
AB	0005515	molecular_function	protein binding
AB	0005739	cellular_component	mitochondrion
AB	0005743	cellular_component	mitochondrial inner membrane
AB	0005763	cellular_component	mitochondrial small ribosomal subunit
AB	0005840	cellular_component	ribosome
AB	0032543	biological_process	mitochondrial translation
AB	1990904	cellular_component	ribonucleoprotein complex
Ac	0001650	cellular_component	fibrillar center
Ac	0003723	molecular_function	RNA binding
Ac	0005515	molecular_function	protein binding
Ac	0005634	cellular_component	nucleus
Ac	0005654	cellular_component	nucleoplasm
Ac	0005739	cellular_component	mitochondrion
Ac	0005743	cellular_component	mitochondrial inner membrane
Ac	0005761	cellular_component	mitochondrial ribosome
Ac	0005840	cellular_component	ribosome
Ac	0032543	biological_process	mitochondrial translation
Ac	1990904	cellular_component	ribonucleoprotein complex
AC	0003723	molecular_function	RNA binding
AC	0003735	molecular_function	structural constituent of ribosome
AC	0005739	cellular_component	mitochondrion
AC	0005743	cellular_component	mitochondrial inner membrane
AC	0005763	cellular_component	mitochondrial small ribosomal subunit
AC	0005840	cellular_component	ribosome
AC	0032543	biological_process	mitochondrial translation
AC	1990904	cellular_component	ribonucleoprotein complex
Ad	0003723	molecular_function	RNA binding
Ad	0003735	molecular_function	structural constituent of ribosome
Ad	0005739	cellular_component	mitochondrion
Ad	0005743	cellular_component	mitochondrial inner membrane
Ad	0005763	cellular_component	mitochondrial small ribosomal subunit
Ad	0005840	cellular_component	ribosome
Ad	0006412	biological_process	translation
Ad	0032543	biological_process	mitochondrial translation
Ad	1990904	cellular_component	ribonucleoprotein complex
AD	0005515	molecular_function	protein binding
AD	0005634	cellular_component	nucleus
AD	0005654	cellular_component	nucleoplasm
AD	0005739	cellular_component	mitochondrion
AD	0005743	cellular_component	mitochondrial inner membrane
AD	0005759	cellular_component	mitochondrial matrix
AD	0005840	cellular_component	ribosome
AD	0032543	biological_process	mitochondrial translation
AD	0045862	biological_process	positive regulation of proteolysis
AD	1990904	cellular_component	ribonucleoprotein complex
Ae	0003723	molecular_function	RNA binding
Ae	0005515	molecular_function	protein binding
Ae	0005739	cellular_component	mitochondrion
Ae	0005743	cellular_component	mitochondrial inner membrane
Ae	0005759	cellular_component	mitochondrial matrix
Ae	0005840	cellular_component	ribosome
Ae	0006417	biological_process	regulation of translation
Ae	0019843	molecular_function	rRNA binding
Ae	0032543	biological_process	mitochondrial translation
Ae	0043024	molecular_function	ribosomal small subunit binding
Ae	1990904	cellular_component	ribonucleoprotein complex
AE	0003735	molecular_function	structural constituent of ribosome
AE	0005515	molecular_function	protein binding
AE	0005739	cellular_component	mitochondrion
AE	0005743	cellular_component	mitochondrial inner membrane
AE	0005763	cellular_component	mitochondrial small ribosomal subunit
AE	0005840	cellular_component	ribosome
AE	0006412	biological_process	translation
AE	0015935	cellular_component	small ribosomal subunit
AE	0019843	molecular_function	rRNA binding
AE	0032543	biological_process	mitochondrial translation
AE	0070181	molecular_function	small ribosomal subunit rRNA binding
AE	1990904	cellular_component	ribonucleoprotein complex
AF	0003723	molecular_function	RNA binding
AF	0003729	molecular_function	mRNA binding
AF	0003735	molecular_function	structural constituent of ribosome
AF	0005739	cellular_component	mitochondrion
AF	0005743	cellular_component	mitochondrial inner membrane
AF	0005763	cellular_component	mitochondrial small ribosomal subunit
AF	0005840	cellular_component	ribosome
AF	0006412	biological_process	translation
AF	0019843	molecular_function	rRNA binding
AF	0032543	biological_process	mitochondrial translation
AF	1990904	cellular_component	ribonucleoprotein complex
Ag	0003723	molecular_function	RNA binding
Ag	0003735	molecular_function	structural constituent of ribosome
Ag	0005515	molecular_function	protein binding
Ag	0005739	cellular_component	mitochondrion
Ag	0005743	cellular_component	mitochondrial inner membrane
Ag	0005763	cellular_component	mitochondrial small ribosomal subunit
Ag	0005840	cellular_component	ribosome
Ag	0006412	biological_process	translation
Ag	0032543	biological_process	mitochondrial translation
Ag	0070013	cellular_component	intracellular organelle lumen
Ag	1990904	cellular_component	ribonucleoprotein complex
AH	0005739	cellular_component	mitochondrion
AH	0005743	cellular_component	mitochondrial inner membrane
AH	0005759	cellular_component	mitochondrial matrix
AH	0005763	cellular_component	mitochondrial small ribosomal subunit
AH	0005840	cellular_component	ribosome
AH	0032543	biological_process	mitochondrial translation
AH	1990904	cellular_component	ribonucleoprotein complex
Ai	0003723	molecular_function	RNA binding
Ai	0003735	molecular_function	structural constituent of ribosome
Ai	0005515	molecular_function	protein binding
Ai	0005739	cellular_component	mitochondrion
Ai	0005743	cellular_component	mitochondrial inner membrane
Ai	0005763	cellular_component	mitochondrial small ribosomal subunit
Ai	0005840	cellular_component	ribosome
Ai	0006412	biological_process	translation
Ai	0032543	biological_process	mitochondrial translation
Ai	1990904	cellular_component	ribonucleoprotein complex
Aj	0003735	molecular_function	structural constituent of ribosome
Aj	0005739	cellular_component	mitochondrion
Aj	0005743	cellular_component	mitochondrial inner membrane
Aj	0005763	cellular_component	mitochondrial small ribosomal subunit
Aj	0005840	cellular_component	ribosome
Aj	0032543	biological_process	mitochondrial translation
Aj	1990904	cellular_component	ribonucleoprotein complex
AJ	0003723	molecular_function	RNA binding
AJ	0003735	molecular_function	structural constituent of ribosome
AJ	0005515	molecular_function	protein binding
AJ	0005739	cellular_component	mitochondrion
AJ	0005743	cellular_component	mitochondrial inner membrane
AJ	0005761	cellular_component	mitochondrial ribosome
AJ	0005763	cellular_component	mitochondrial small ribosomal subunit
AJ	0005840	cellular_component	ribosome
AJ	0006412	biological_process	translation
AJ	0015935	cellular_component	small ribosomal subunit
AJ	0032543	biological_process	mitochondrial translation
AJ	1990904	cellular_component	ribonucleoprotein complex
AK	0003723	molecular_function	RNA binding
AK	0003735	molecular_function	structural constituent of ribosome
AK	0005515	molecular_function	protein binding
AK	0005737	cellular_component	cytoplasm
AK	0005739	cellular_component	mitochondrion
AK	0005743	cellular_component	mitochondrial inner membrane
AK	0005761	cellular_component	mitochondrial ribosome
AK	0005763	cellular_component	mitochondrial small ribosomal subunit
AK	0005840	cellular_component	ribosome
AK	0006412	biological_process	translation
AK	0032543	biological_process	mitochondrial translation
AK	1990904	cellular_component	ribonucleoprotein complex
AL	0003723	molecular_function	RNA binding
AL	0003735	molecular_function	structural constituent of ribosome
AL	0005515	molecular_function	protein binding
AL	0005739	cellular_component	mitochondrion
AL	0005743	cellular_component	mitochondrial inner membrane
AL	0005759	cellular_component	mitochondrial matrix
AL	0005761	cellular_component	mitochondrial ribosome
AL	0005763	cellular_component	mitochondrial small ribosomal subunit
AL	0005840	cellular_component	ribosome
AL	0006412	biological_process	translation
AL	0032543	biological_process	mitochondrial translation
AL	1990904	cellular_component	ribonucleoprotein complex
AM	0003735	molecular_function	structural constituent of ribosome
AM	0005515	molecular_function	protein binding
AM	0005739	cellular_component	mitochondrion
AM	0005743	cellular_component	mitochondrial inner membrane
AM	0005763	cellular_component	mitochondrial small ribosomal subunit
AM	0005840	cellular_component	ribosome
AM	0006412	biological_process	translation
AM	0032543	biological_process	mitochondrial translation
AM	1990904	cellular_component	ribonucleoprotein complex
AN	0003723	molecular_function	RNA binding
AN	0003735	molecular_function	structural constituent of ribosome
AN	0005739	cellular_component	mitochondrion
AN	0005743	cellular_component	mitochondrial inner membrane
AN	0005763	cellular_component	mitochondrial small ribosomal subunit
AN	0005840	cellular_component	ribosome
AN	0006412	biological_process	translation
AN	0019843	molecular_function	rRNA binding
AN	0032543	biological_process	mitochondrial translation
AN	1990904	cellular_component	ribonucleoprotein complex
AO	0003735	molecular_function	structural constituent of ribosome
AO	0005739	cellular_component	mitochondrion
AO	0005743	cellular_component	mitochondrial inner membrane
AO	0005763	cellular_component	mitochondrial small ribosomal subunit
AO	0005840	cellular_component	ribosome
AO	0006412	biological_process	translation
AO	0032543	biological_process	mitochondrial translation
AO	1990904	cellular_component	ribonucleoprotein complex
AP	0003735	molecular_function	structural constituent of ribosome
AP	0005739	cellular_component	mitochondrion
AP	0005743	cellular_component	mitochondrial inner membrane
AP	0005763	cellular_component	mitochondrial small ribosomal subunit
AP	0005840	cellular_component	ribosome
AP	0006412	biological_process	translation
AP	0032543	biological_process	mitochondrial translation
AP	0070181	molecular_function	small ribosomal subunit rRNA binding
AP	1990904	cellular_component	ribonucleoprotein complex
AQ	0003723	molecular_function	RNA binding
AQ	0003735	molecular_function	structural constituent of ribosome
AQ	0005739	cellular_component	mitochondrion
AQ	0005743	cellular_component	mitochondrial inner membrane
AQ	0005763	cellular_component	mitochondrial small ribosomal subunit
AQ	0005840	cellular_component	ribosome
AQ	0006412	biological_process	translation
AQ	0032543	biological_process	mitochondrial translation
AQ	1990904	cellular_component	ribonucleoprotein complex
AR	0003735	molecular_function	structural constituent of ribosome
AR	0005515	molecular_function	protein binding
AR	0005739	cellular_component	mitochondrion
AR	0005743	cellular_component	mitochondrial inner membrane
AR	0005761	cellular_component	mitochondrial ribosome
AR	0005763	cellular_component	mitochondrial small ribosomal subunit
AR	0005840	cellular_component	ribosome
AR	0032543	biological_process	mitochondrial translation
AR	1990904	cellular_component	ribonucleoprotein complex
AS	0003723	molecular_function	RNA binding
AS	0003735	molecular_function	structural constituent of ribosome
AS	0005515	molecular_function	protein binding
AS	0005739	cellular_component	mitochondrion
AS	0005743	cellular_component	mitochondrial inner membrane
AS	0005840	cellular_component	ribosome
AS	0006412	biological_process	translation
AS	0032543	biological_process	mitochondrial translation
AS	1990904	cellular_component	ribonucleoprotein complex
AT	0003735	molecular_function	structural constituent of ribosome
AT	0005739	cellular_component	mitochondrion
AT	0005743	cellular_component	mitochondrial inner membrane
AT	0005840	cellular_component	ribosome
AT	0032543	biological_process	mitochondrial translation
AT	1990904	cellular_component	ribonucleoprotein complex
AU	0003723	molecular_function	RNA binding
AU	0005739	cellular_component	mitochondrion
AU	0005743	cellular_component	mitochondrial inner membrane
AU	0005763	cellular_component	mitochondrial small ribosomal subunit
AU	0005840	cellular_component	ribosome
AU	0032543	biological_process	mitochondrial translation
AU	1990904	cellular_component	ribonucleoprotein complex
AV	0000049	molecular_function	tRNA binding
AV	0003723	molecular_function	RNA binding
AV	0005515	molecular_function	protein binding
AV	0005737	cellular_component	cytoplasm
AV	0005739	cellular_component	mitochondrion
AV	0005743	cellular_component	mitochondrial inner membrane
AV	0005763	cellular_component	mitochondrial small ribosomal subunit
AV	0005840	cellular_component	ribosome
AV	0006417	biological_process	regulation of translation
AV	0008283	biological_process	cell population proliferation
AV	0019843	molecular_function	rRNA binding
AV	0032543	biological_process	mitochondrial translation
AV	1990904	cellular_component	ribonucleoprotein complex
AW	0003723	molecular_function	RNA binding
AW	0005739	cellular_component	mitochondrion
AW	0005743	cellular_component	mitochondrial inner membrane
AW	0005763	cellular_component	mitochondrial small ribosomal subunit
AW	0005840	cellular_component	ribosome
AW	0032543	biological_process	mitochondrial translation
AW	1990904	cellular_component	ribonucleoprotein complex
AX	0000166	molecular_function	nucleotide binding
AX	0003723	molecular_function	RNA binding
AX	0003735	molecular_function	structural constituent of ribosome
AX	0003924	molecular_function	GTPase activity
AX	0005515	molecular_function	protein binding
AX	0005525	molecular_function	GTP binding
AX	0005654	cellular_component	nucleoplasm
AX	0005739	cellular_component	mitochondrion
AX	0005743	cellular_component	mitochondrial inner membrane
AX	0005759	cellular_component	mitochondrial matrix
AX	0005761	cellular_component	mitochondrial ribosome
AX	0005763	cellular_component	mitochondrial small ribosomal subunit
AX	0005840	cellular_component	ribosome
AX	0006915	biological_process	apoptotic process
AX	0015935	cellular_component	small ribosomal subunit
AX	0016787	molecular_function	hydrolase activity
AX	0032543	biological_process	mitochondrial translation
AX	0097190	biological_process	apoptotic signaling pathway
AX	1990904	cellular_component	ribonucleoprotein complex
AY	0003723	molecular_function	RNA binding
AY	0003735	molecular_function	structural constituent of ribosome
AY	0005515	molecular_function	protein binding
AY	0005739	cellular_component	mitochondrion
AY	0005743	cellular_component	mitochondrial inner membrane
AY	0005763	cellular_component	mitochondrial small ribosomal subunit
AY	0005840	cellular_component	ribosome
AY	0019904	molecular_function	protein domain specific binding
AY	0032543	biological_process	mitochondrial translation
AY	1990904	cellular_component	ribonucleoprotein complex
AZ	0003735	molecular_function	structural constituent of ribosome
AZ	0005739	cellular_component	mitochondrion
AZ	0005743	cellular_component	mitochondrial inner membrane
AZ	0005763	cellular_component	mitochondrial small ribosomal subunit
AZ	0005840	cellular_component	ribosome
AZ	0006412	biological_process	translation
AZ	0032543	biological_process	mitochondrial translation
AZ	1990904	cellular_component	ribonucleoprotein complex
Bd	0003735	molecular_function	structural constituent of ribosome
Bd	0005739	cellular_component	mitochondrion
Bd	0005743	cellular_component	mitochondrial inner membrane
Bd	0005762	cellular_component	mitochondrial large ribosomal subunit
Bd	0005840	cellular_component	ribosome
Bd	0006412	biological_process	translation
Bd	0032543	biological_process	mitochondrial translation
Bd	1990904	cellular_component	ribonucleoprotein complex
BX	0003735	molecular_function	structural constituent of ribosome
BX	0005515	molecular_function	protein binding
BX	0005634	cellular_component	nucleus
BX	0005739	cellular_component	mitochondrion
BX	0005743	cellular_component	mitochondrial inner membrane
BX	0005762	cellular_component	mitochondrial large ribosomal subunit
BX	0005840	cellular_component	ribosome
BX	0006412	biological_process	translation
BX	0032543	biological_process	mitochondrial translation
BX	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAnR

Chain	Residue	Details
AJ	LYS71-ARG78

site_id	PS00057
Number of Residues	25
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. VDYkn.VqlLsqFVSPftGCIygrHI

Chain	Residue	Details
AP	VAL72-ILE96

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGrsAQagAirlAmAKAL

Chain	Residue	Details
Ag	GLY334-LEU352

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRkksIrVlvAVGNgk.GaAGfSigkat.DRmd.AF

Chain	Residue	Details
Ad	GLY236-PHE268

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VrSLFDARVHLG

Chain	Residue	Details
Ab	VAL81-GLY92

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	64
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	9
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	80
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	68
Details	Repeat: {"description":"PPR 1"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	35
Details	Repeat: {"description":"PPR 2"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	30
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25838379","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	10
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	64
Details	Region: {"description":"GGQ domain","evidences":[{"source":"UniProtKB","id":"Q80VP5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	2
Details	Motif: {"description":"GGQ","evidences":[{"source":"PubMed","id":"37141370","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"source":"PubMed","id":"35260756","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	42
Details	Domain: {"description":"CHCH","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	10
Details	Motif: {"description":"Cx9C motif 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	10
Details	Motif: {"description":"Cx9C motif 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	64
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00268","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	34
Details	Repeat: {"description":"PPR 3"}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	40
Details	Repeat: {"description":"PPR 4"}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	36
Details	Repeat: {"description":"PPR 5"}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	41
Details	Repeat: {"description":"PPR 6"}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	34
Details	Repeat: {"description":"PPR 7"}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	34
Details	Repeat: {"description":"PPR 8"}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	34
Details	Repeat: {"description":"PPR 9"}

Chain

Residue

Details

site_id	SWS_FT_FI25
Number of Residues	34
Details	Repeat: {"description":"PPR 10"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)