8OIO
Crystal structure of the kelch domain of human KLHL12 in complex with PLEKHA4 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Kelch-like protein 12 | polymer | 301 | 32905.9 | 4 | UniProt (Q53G59) Pfam (PF01344) | Homo sapiens (human) | CUL3-interacting protein 1,DKIR homolog,hDKIR |
| 2 | E, F, G, H (F, G, H, E) | Pleckstrin homology domain-containing family A member 4 | polymer | 11 | 950.0 | 4 | UniProt (Q9H4M7) | Homo sapiens | PH domain-containing family A member 4,Phosphoinositol 3-phosphate-binding protein 1,PEPP-1 |
| 3 | I, N, O, P, Q (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | J (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | K, L, M (B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 6 | R, S, T, U, V... (A, B, C, D, F...) | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 268 - 567 (UniProt: Q53G59)
| PDB | External Database | Details |
|---|---|---|
| Ser 267 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 135423.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 414.8 | |
| All* | Total formula weight | 135838.3 |
