8OIJ

Drosophila Smaug-Smoothened complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein Smaug	polymer	177	19964.8	2	UniProt (Q23972)	Drosophila melanogaster (fruit fly)
2	C, D (C, D)	Protein smoothened	polymer	35	3816.1	2	UniProt (P91682)	Drosophila melanogaster (fruit fly)	dSMO,SMOH,Smooth
3	E, G (A, D)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	F (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
5	H, I, J, K (A, B, C, D)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

A, B: 73 - 155 (UniProt: Q23972)

PDB	External Database	Details
Gly 61	-	expression tag
Gly 62	-	expression tag
Ser 63	-	expression tag
Gly 64	-	expression tag
Gly 65	-	expression tag
Ser 66	-	expression tag
Gly 67	-	expression tag
Gly 68	-	expression tag
Ser 69	-	expression tag
Gly 70	-	expression tag
Gly 71	-	expression tag
Ser 72	-	expression tag

A, B: 197 - 278 (UniProt: Q23972)
C, D: 970 - 1003 (UniProt: P91682)

PDB	External Database	Details
Ser 969	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	47561.8
Non-Polymers*	Number of molecules	3
	Total formula weight	230.3
All*	Total formula weight	47792.1

*Water molecules are not included.