8OGE
Structure of cobalt(II) substituted double mutant human carbonic anhydrase II bound to thiocyanate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29241.0 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II,Cyanamide hydratase CA2 |
| 2 | B (A) | 4-(HYDROXYMERCURY)BENZOIC ACID | non-polymer | 338.7 | 1 | Chemie (HGB) | |||
| 3 | C (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 4 | D (A) | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 5 | E (A) | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Asn 3 | His 3 | engineered mutation |
| Asn 4 | His 4 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29241.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 455.7 | |
| All* | Total formula weight | 29696.7 |
