8ODP

Structure of human RTCB with GMPCPP in complex with Archease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	RNA-splicing ligase RtcB homolog	polymer	507	55412.3	4	UniProt (Q9Y3I0) Pfam (PF01139) In PDB	Homo sapiens (human)	3'-phosphate/5'-hydroxy nucleic acid ligase
2	B, D, F, H	Protein archease	polymer	183	21108.6	4	UniProt (A8K0B5) Pfam (PF01951) In PDB	Homo sapiens (human)
3	A, B, C, D, E...	MANGANESE (II) ION	non-polymer		54.9	12	Chemie (MN)
4	A, C, E, G	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	4	Chemie (G2P)
5		water	water		18.0	297	Chemie (HOH)

Sequence modifications

A, C, E, G: 1 - 505 (UniProt: Q9Y3I0)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

B, D, F, H: 1 - 179 (UniProt: A8K0B5)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	306083.5
Non-Polymers*	Number of molecules	16
	Total formula weight	2744.1
All*	Total formula weight	308827.6

*Water molecules are not included.