8KI4
Crystal structure of human HSP90 in intermediate state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Heat shock protein HSP 90-alpha | polymer | 241 | 27337.6 | 2 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (human) | Heat shock 86 kDa,HSP 86,HSP86,Lipopolysaccharide-associated protein 2,LAP-2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
3 | water | water | 18.0 | 466 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 236 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
Glu 2 | - | expression tag |
Asn 3 | - | expression tag |
Leu 4 | - | expression tag |
Tyr 5 | - | expression tag |
Phe 6 | - | expression tag |
Gln 7 | - | expression tag |
Gly 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 54675.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 124.1 | |
All* | Total formula weight | 54799.3 |