8K97
CryoEM structure of LonC protease hexamer with Bortezomib
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... (A, F, E, D, C...) | endopeptidase La | polymer | 732 | 80558.4 | 6 | UniProt (C9DRU9) Pfam (PF13654) Pfam (PF20436) Pfam (PF05362) | Meiothermus taiwanensis | LonC protease |
2 | G, I, K, M, O... (A, F, E, D, C...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
3 | H, J, L, N, P... (A, F, E, D, C...) | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | non-polymer | 384.2 | 6 | Chemie (BO2) |
Sequence modifications
A, F, E, D, C, B: 1 - 719 (UniProt: C9DRU9)
PDB | External Database | Details |
---|---|---|
Lys 720 | - | expression tag |
Leu 721 | - | expression tag |
Ala 722 | - | expression tag |
Ala 723 | - | expression tag |
Ala 724 | - | expression tag |
Leu 725 | - | expression tag |
Glu 726 | - | expression tag |
His 727 | - | expression tag |
His 728 | - | expression tag |
His 729 | - | expression tag |
His 730 | - | expression tag |
His 731 | - | expression tag |
His 732 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 483350.1 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 2875.2 | |
All* | Total formula weight | 486225.4 |