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8K97

CryoEM structure of LonC protease hexamer with Bortezomib

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, F, E, D, C...)
endopeptidase Lapolymer73280558.46UniProt (C9DRU9)
Pfam (PF13654)
Pfam (PF20436)
Pfam (PF05362)
Meiothermus taiwanensisLonC protease
2G, I, K, M, O...
(A, F, E, D, C...)
PHOSPHATE IONnon-polymer95.06Chemie (PO4)
3H, J, L, N, P...
(A, F, E, D, C...)
N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDEnon-polymer384.26Chemie (BO2)
Sequence modifications
A, F, E, D, C, B: 1 - 719 (UniProt: C9DRU9)
PDBExternal DatabaseDetails
Lys 720-expression tag
Leu 721-expression tag
Ala 722-expression tag
Ala 723-expression tag
Ala 724-expression tag
Leu 725-expression tag
Glu 726-expression tag
His 727-expression tag
His 728-expression tag
His 729-expression tag
His 730-expression tag
His 731-expression tag
His 732-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight483350.1
Non-Polymers*Number of molecules12
Total formula weight2875.2
All*Total formula weight486225.4
*Water molecules are not included.

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PDB entries from 2024-11-13

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