8K7T

Mouse Fc epsilon RI in complex with mIgE Fc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	High affinity immunoglobulin epsilon receptor subunit alpha	polymer	273	31646.2	1	UniProt (P20489) Pfam (PF13895)	Mus musculus (house mouse)
2	B, C (G, H)	High affinity immunoglobulin epsilon receptor subunit gamma	polymer	104	11890.9	2	UniProt (P20491) Pfam (PF11628) Pfam (PF02189)	Mus musculus (house mouse)
3	D (B)	High affinity immunoglobulin epsilon receptor subunit beta	polymer	245	27166.1	1	UniProt (P20490) Pfam (PF04103)	Mus musculus (house mouse)
4	E, F (E, F)	IgE Fc	polymer	356	40369.7	2	Pfam (PF07654) Pfam (PF00047) UniProt (by SIFTS) (P06336)	Mus musculus
5	G, H (C, D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
6	I, J (I, J)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
7	K, L, M, N, O... (A, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)

Sequence modifications

A: 1 - 250 (UniProt: P20489)

PDB	External Database	Details
Glu 251	-	expression tag
Asn 252	-	expression tag
Leu 253	-	expression tag
Tyr 254	-	expression tag
Phe 255	-	expression tag
Gln 256	-	expression tag
Gly 257	-	expression tag
Asp 258	-	expression tag
Tyr 259	-	expression tag
Lys 260	-	expression tag
Asp 261	-	expression tag
Asp 262	-	expression tag
Asp 263	-	expression tag
Asp 264	-	expression tag
Lys 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag

G, H: 1 - 86 (UniProt: P20491)

PDB	External Database	Details
Trp 87	-	expression tag
Ser 88	-	expression tag
His 89	-	expression tag
Pro 90	-	expression tag
Gln 91	-	expression tag
Phe 92	-	expression tag
Glu 93	-	expression tag
Lys 94	-	expression tag
Glu 95	-	expression tag
Gln 96	-	expression tag
Lys 97	-	expression tag
Leu 98	-	expression tag
Ile 99	-	expression tag
Ser 100	-	expression tag
Glu 101	-	expression tag
Glu 102	-	expression tag
Asp 103	-	expression tag
Leu 104	-	expression tag

B: 1 - 235 (UniProt: P20490)

PDB	External Database	Details
Glu 236	-	expression tag
Gln 237	-	expression tag
Lys 238	-	expression tag
Leu 239	-	expression tag
Ile 240	-	expression tag
Ser 241	-	expression tag
Glu 242	-	expression tag
Glu 243	-	expression tag
Asp 244	-	expression tag
Leu 245	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	163333.5
Branched	Number of molecules	4
	Total formula weight	2994.7
Non-Polymers*	Number of molecules	7
	Total formula weight	1548.5
All*	Total formula weight	167876.7

*Water molecules are not included.