8K73
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((1-(phenylsulfonyl)pyrrolidine-3-carbonyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 349 | 40328.3 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
| 2 | B, C, M, N, O... (A) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 3 | D, E, F, G, H... (A) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | K (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | L (A) | 2-[(2~{Z})-3-oxidanyl-2-[(3~{R})-1-(phenylsulfonyl)pyrrolidin-3-yl]carbonylimino-1,3-thiazol-4-yl]ethanoic acid | non-polymer | 411.5 | 1 | Chemie (VK6) | |||
| 6 | R (A) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40328.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1794.0 | |
| All* | Total formula weight | 42122.2 |
