8K1V

Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4, 5 mM KCl and 135 mM NaCl

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Potassium channel subfamily K member 9	polymer	275	31173.2	2	UniProt (Q9NPC2) Pfam (PF07885)	Homo sapiens (human)	Acid-sensitive potassium channel protein TASK-3,TWIK-related acid-sensitive K(+) channel 3,Two pore potassium channel KT3.2,Two pore K(+) channel KT3.2
2	C, D, E, K, L... (A, B)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	6	Chemie (Y01)
3	F, G, H, I, J (A)	POTASSIUM ION	non-polymer		39.1	5	Chemie (K)
4	N, O (A, B)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B: 1 - 259 (UniProt: Q9NPC2)

PDB	External Database	Details
Asn 260	-	expression tag
Leu 261	-	expression tag
Tyr 262	-	expression tag
Phe 263	-	expression tag
Gln 264	-	expression tag
Gly 265	-	expression tag
Val 266	-	expression tag
Asp 267	-	expression tag
Ala 268	-	expression tag
Gly 269	-	expression tag
Leu 270	-	expression tag
Glu 271	-	expression tag
Val 272	-	expression tag
Leu 273	-	expression tag
Phe 274	-	expression tag
Gln 275	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62346.5
Non-Polymers*	Number of molecules	11
	Total formula weight	3115.8
All*	Total formula weight	65462.3

*Water molecules are not included.