8K18
Neutralization antibody ZCP4C9 bound with SARS-CoV-2 Omicron BA.5 RBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Spike protein S1 | polymer | 193 | 21833.6 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (C) | ZCP4C9 heavy chain | polymer | 119 | 13220.7 | 1 | Homo sapiens (human) | ||
| 3 | C (D) | ZCP4C9 light chain | polymer | 107 | 11521.7 | 1 | Homo sapiens (human) |
Sequence modifications
E: 334 - 526 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Asp 339 | Gly 339 | variant |
| Lys 346 | Arg 346 | conflict |
| Pro 348 | Ala 348 | conflict |
| Glu 354 | Asn 354 | conflict |
| Lys 357 | Arg 357 | conflict |
| Phe 371 | Ser 371 | variant |
| Thr 372 | Ala 372 | conflict |
| Pro 373 | Ser 373 | variant |
| Phe 375 | Ser 375 | variant |
| Ala 376 | Thr 376 | variant |
| Ala 384 | Pro 384 | conflict |
| Ser 393 | Thr 393 | conflict |
| Val 402 | Ile 402 | conflict |
| Lys 403 | Arg 403 | conflict |
| Asp 406 | Glu 406 | conflict |
| Ser 408 | Arg 408 | variant |
| Asn 417 | Lys 417 | variant |
| Met 430 | Thr 430 | conflict |
| Leu 434 | Ile 434 | conflict |
| Thr 438 | Ser 438 | conflict |
| Arg 439 | Asn 439 | conflict |
| Lys 440 | Asn 440 | variant |
| Ile 441 | Leu 441 | conflict |
| Ala 443 | Ser 443 | conflict |
| Thr 444 | Lys 444 | conflict |
| Ser 445 | Val 445 | conflict |
| Thr 446 | Gly 446 | conflict |
| Arg 452 | Leu 452 | variant |
| Asn 477 | Ser 477 | variant |
| Lys 478 | Thr 478 | variant |
| Ala 484 | Glu 484 | variant |
| Val 486 | Phe 486 | variant |
| Ser 496 | Gly 496 | conflict |
| Arg 498 | Gln 498 | variant |
| Tyr 501 | Asn 501 | variant |
| His 505 | Tyr 505 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46576.1 | |
| All* | Total formula weight | 46576.1 |
